Ketogenic Diet Revisited in the Laboratory

Ketogenic diet in epileptic children: clinical and laboratory assessment.

Epilepsy is the most frequent neurological pathology in children, and in some cases it has no adequate control with drug treatments. The improvement of epilepsy control observed during starvation periods triggered the development of a diet that simulates its alterations, allowing its use to treat difficult to control epileptic patients. Many researchers have been demonstrating the efficacy of t...

The Ketogenic Diet

Optic neuropathy in ketogenic diet.

A symmetrical, bilateral optic neuropathy is reported in 2 patients being treated with ketogenic diets for seizure control. Laboratory tests suggested a thiamine deficiency, and both patients recovered normal visual function after several weeks of treatment with thiamine. The risk of optic nerve dysfunction occurring during the treatment with a ketogenic diet can be minimised if routine vitamin...

Ketogenic Diet in Epileptic Encephalopathies

The ketogenic diet is a medically supervised high-fat, low-carbohydrate diet that has been found useful in patients with refractory epilepsy. It has been shown to be effective in treating multiple seizure types and epilepsy syndromes. In this paper, we review the use of the ketogenic diet in epileptic encephalopathies such as Ohtahara syndrome, West syndrome, Dravet syndrome, epilepsy with myoc...

Ketogenic Diet in Seizure Disorders

The ketogenic diet (KD) has been used successfully in a variety of epilepsy syndromes. This includes syndromes with multiple etiologies, including Lennox-Gastaut syndrome and infantile spasms; developmental syndromes of unknown etiology, such as Landau-Kleffner syndrome; and idiopathic epilepsies, such as myoclonic-astatic (Doose) epilepsy. It also includes syndromes where genetics play a major...